212841-97-9Relevant academic research and scientific papers
Synthesis of the benz[a]anthraquinone core of angucyclinone antibiotics
Kalogerakis, Aris,Groth, Ulrich
, p. 843 - 844 (2003)
A general method for the synthesis of benz[a]anthraquinones is reported. The key step is a catalytic cobalt-mediated [2+2+2]-cycloaddition of a triyne, which affords an angularly substituted tetracycle. Oxidation of this core gives the typical structure o
The cobalt way to angucyclinones: Asymmetric total synthesis of the antibiotics (+)-rubiginone B2, (-)-tetrangomycin, and ( - ) -8- O-Methyltetrangomycin
Kesenheimer, Christian,Kalogerakis, Aris,Meissner, Anja,Groth, Ulrich
experimental part, p. 8805 - 8821 (2010/10/21)
A cobalt(I)-mediated convergent and asymmetric total synthesis of angucyclinones with an aromatic B ring has been developed. In the course of our research, we synthesized three naturally occurring anguclinone derivatives, namely, (+)-rubiginone B2/s
