212913-13-8

Usage

Uses

Used in Pharmaceutical Synthesis:
Carbamic acid, [(2-oxo-5-oxazolidinyl)methyl]-, 1,1-dimethylethyl ester (9CI) is used as a key intermediate in the synthesis of pharmaceuticals. Its unique structure and reactivity make it a valuable component in the development of new drugs and medicinal compounds.
Used in Agricultural Chemical Synthesis:
Carbamic acid, [(2-oxo-5-oxazolidinyl)methyl]-, 1,1-dimethylethyl ester (9CI) is also utilized in the synthesis of agricultural chemicals, contributing to the development of more effective and safer products for crop protection and other agricultural applications.
Used as a Reagent in Chemical Research:
Carbamic acid, [(2-oxo-5-oxazolidinyl)methyl]-, 1,1-dimethylethyl ester (9CI) serves as a reagent in various chemical research applications. Its mild and selective reactivity allows for precise manipulation and synthesis of complex organic compounds, facilitating advancements in the field of chemistry.
Used in Other Organic Compound Synthesis:
In addition to its applications in pharmaceuticals and agricultural chemicals, this ester is also used in the synthesis of other organic compounds. Its versatility and unique properties make it a valuable asset in the development of new materials and chemical products.

Upstream product

• 917824-22-7 (1'S,5S)-5-tert-butoxycarbonylaminomethyl-3-(1'-phenylethyl)-1,3-oxazolidin-2-one 
• 917824-20-5 (1'S,5R)-5-tert-butoxycarbonylaminomethyl-3-(1'-phenylethyl)-1,3-oxazolidin-2-one 
• 98642-15-0 (3-tert-butoxycarbonylamino-2-hydroxy-propyl)-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Synthesis of enantiomerically pure (+)- and (-)-protected 5-aminomethyl-1,3-oxazolidin-2-one derivatives from allylamine and carbon dioxide

The stereoselective synthesis of enantiomerically pure (5R)- and (5S)-aminomethyl-oxazolidinones with different protecting groups have been carried out from an allyl amine as the source of the carbon backbone. The key reaction is the high yield iodiocyclization of enantiomerically pure allylphenethyl amine in the presence of carbon dioxide.

Process for preparing optically active oxazolidinone derivative

Disclosed is a process for preparing an optically active oxazolidinone derivative comprising allowing hydrazine to react on an optically active ester having a hydroxyl group at the 3-position which is represented by formula (II): wherein R1represents a lower alkyl group having 1 to 4 carbon atoms, a phenyl group, a methoxymethyl group, a benzyloxymethyl group, a benzyloxycarbonylaminomethyl group which may have a substituent or substituents on the benzene ring thereof, an acylaminomethyl group having 3 to 10 carbon atoms, or an alkyloxycarbonylaminomethyl group having 3 to 6 carbon atoms; R2and R3, which may be the same or different, each represent a hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms, a phenyl group, an acetylaminomethyl group, a benzoylaminomethyl group, or a benzyl group; and * indicates an asymmetric carbon atom, and subjecting the resulting hydrazide to Curtius rearrangement.

Solution parallel synthesis of cyclic guanidines

An efficient method for the solution phase synthesis of cyclic guanidines is presented. A variety of 2-substituted monoprotected propanediamines react with a set of 5-substituted 2-methylthio-3,4,5,6- tetrahydropyrimidines under Rathke conditions for the construction of a potential library of 81 cyclic guanidines.

Lipophilic Propanediamines: New Building Blocks for Combinatorial Chemistry

Combinatorial chemists need building block libraries where molecular diversity is taken into account.For this purpose, we describe the synthesis of a library of 2-alkyl and 2-alkoxypropanediamines for which a large scale of lipophilicity is investigated.