212913-17-2Relevant academic research and scientific papers
Solution parallel synthesis of cyclic guanidines
Marmillon, Christelle,Bompart, Jacques,Calas, Michèle,Escale, Roger,Bonnet, Pierre-Antoine
, p. 1317 - 1328 (2007/10/03)
An efficient method for the solution phase synthesis of cyclic guanidines is presented. A variety of 2-substituted monoprotected propanediamines react with a set of 5-substituted 2-methylthio-3,4,5,6- tetrahydropyrimidines under Rathke conditions for the construction of a potential library of 81 cyclic guanidines.
Lipophilic Propanediamines: New Building Blocks for Combinatorial Chemistry
Marmillon, C.,Jerosch, H.,Bompart, J.,Calas, M.,Bonnet, P. A.,Escale, R.
, p. 6178 - 6180 (2007/10/03)
Combinatorial chemists need building block libraries where molecular diversity is taken into account.For this purpose, we describe the synthesis of a library of 2-alkyl and 2-alkoxypropanediamines for which a large scale of lipophilicity is investigated.
