213010-61-8Relevant academic research and scientific papers
Synthesis of a high-mannose-type glycopeptide analog containing a glucose-asparagine linkage
Deras, Ina L.,Takegawa, Kaoru,Kondo, Akihiro,Kato, Ikunoshin,Lee, Yuan C.
, p. 1763 - 1766 (2007/10/03)
The title compound was prepared by enzymatic transfer of oligosaccharide to a synthetic pentapeptide containing the Glc-Asn linkage. The compound was not hydrolyzed by glycoamidases from plant and bacterial sources, but it inhibited both enzymes in the micromolar range. Its activity is compared to other potential inhibitors.
