213012-84-1Relevant academic research and scientific papers
Hydroxamic and carboxylic acid derivatives
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, (2008/06/13)
The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with matrix metalloproteinase, ADAM or ADAM-TS enzymes, a condition that is mediated by TNF α or a condition involving a membrane-shedding ev
Synthesis and activity of selective MMP inhibitors with an aryl backbone
E. Barta, Thomas,P. Becker, Daniel,J. Bedell, Louis,A. De Crescenzo, Gary,J. McDonald, Joseph,E. Munie, Grace,Rao, Shashi,Shieh, Huey-Sheng,Stegeman, Roderick,M. Stevens, Anna,I. Villamil, Clara
, p. 2815 - 2817 (2007/10/03)
A series of novel, MMP-1 sparing arylhydroxamate sulfonamides with activity against MMP-2 and -13 is described. (C) 2000 Elsevier Science Ltd.
