213014-58-5Relevant academic research and scientific papers
A short enantioselective access to 2,3,6-trialkylpiperidines and 5,8- dialkylindolizidines
Wong, Yung-Sing,Gnecco, Dino,Marazano, Christian,Chiaroni, Angele,Riche, Claude,Billion, Annick,Das, Bhupesh C.
, p. 9357 - 9372 (2007/10/03)
An enantioselective access to 2,3,6-trialkylpiperidines 5 is described. This sequence is illustrated by the four-step syntheses, from salts 1, of piperidine 6 and indolizidines 7 and 8. The overall yields are in the range 10-15%. The stereochemistry of in
