21306-56-9

Basic information

• Product Name: QX-314
• Synonyms: 2-[(2,6-Dimethylphenyl)amino]-N,N,N-triethyl-2-oxoethanaminium;QX-314.Br;QX-314 bromide (N-Ethyllidocaine bromide);N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM BROMIDE;N-(2,6-DIMETHYLPHENYL)ACETAMIDE-2-TRIETHYLAMMONIUM BROMIDE;QX-314;QX 314 BROMIDE;LIDOCAINE N-ETHYL BROMIDE
• CAS NO: 21306-56-9
• Molecular Formula: C16H27BrN2O
• Molecular Weight: 343.3
• Product Categories: Sodium channel;Ion Channels
• Mol File: 21306-56-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Desiccate at RT
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: QX-314(CAS DataBase Reference)
• NIST Chemistry Reference: QX-314(21306-56-9)
• EPA Substance Registry System: QX-314(21306-56-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 21306-56-9(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 21306-56-9 differently. You can refer to the following data:
1. Blocker of voltage-activated sodium channels
2. QX-314 bromide is a derivative of Lidocaine. It is a local anesthetic.

Biological Activity

Membrane impermeable quaternary derivative of lidocaine, a blocker of voltage-activated Na + channels. Intracellular QX 314 bromide also inhibits calcium currents in hippocampal CA1 pyramidal neurons.

InChI:InChI=1/C16H26N2O.BrH/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5;/h9-11H,6-8,12H2,1-5H3;1H