213182-13-9

Upstream product

• 144446-48-0 (E)-3-[(2R,5S,6R,9R)-2-tert-Butyl-8-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-4-oxo-1,3-dioxa-spiro[4.5]dec-7-en-6-yl]-acrylic acid methyl ester 
• 146983-23-5 4-{[(tert-butyldiphenylsilyl)oxy]methyl}-2(E),4(Z)-hexadienal 
• 144446-46-8 (2E,4E,6Z)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-octa-2,4,6-trienoic acid methyl ester 
• 130930-48-2 (2R)-2-tert-butyl-5-methylene-1,3-dioxolan-4-one 

Downstream Products

• 213182-20-8 (1S,2R,5R)-2-[(E)-3-(tert-Butyl-dimethyl-silanyloxy)-propenyl]-4-(tert-butyl-diphenyl-silanyloxymethyl)-1-hydroxy-5-methyl-cyclohex-3-enecarboxylic acid methyl ester 
• 144446-50-4 (2R,5S,6R,9R)-2-tert-Butyl-6-[(E)-3-(tert-butyl-dimethyl-silanyloxy)-propenyl]-8-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-1,3-dioxa-spiro[4.5]dec-7-en-4-one 
• 144446-51-5 (1S,2R,5R)-1-(2-Benzyloxy-acetoxy)-2-[(E)-3-(tert-butyl-dimethyl-silanyloxy)-propenyl]-4-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-cyclohex-3-enecarboxylic acid methyl ester 
• 144476-53-9 (5S,6R,9R)-3-Benzyloxy-6-[(E)-3-(tert-butyl-dimethyl-silanyloxy)-propenyl]-8-(tert-butyl-diphenyl-silanyloxymethyl)-4-methoxymethoxy-9-methyl-1-oxa-spiro[4.5]deca-3,7-dien-2-one 
• 213182-14-0 (2R,5S,6R,9R)-2-tert-Butyl-6-[(E)-3-(tert-butyl-dimethyl-silanyloxy)-propenyl]-8-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-1,3-dioxa-spiro[4.5]dec-7-en-4-ol 

Relevant academic research and scientific papers

Studies on the synthesis of chlorothricolide: Diastereo- and enantioselective syntheses of model top-half spirotetronate units

Highly enantio- and diastereoselective syntheses of spirotetronates 9 and 10, corresponding to the top-half fragment of chlorothricolide, are described. Key steps in these syntheses are the Diels-Alder reactions of trienes 11 and 12 with the chiral dienop

Enantioselective Synthesis of the Top Half of Chlorothricolide

Highly enantio- and diastereoselective syntheses of spirotetronates 4 and 5 corresponding to the top half of chlorothricolide are described.