(4Z,6Z,8E)-Cyclohepta[b]pyrrol-2(1H)-one, also known as norbelladine, is a heterocyclic compound characterized by a seven-membered ring structure that includes a nitrogen atom. This cyclic ketone derivative and pyrrolidone compound are found in natural products such as Amaryllidaceae alkaloids. Norbelladine has been utilized as a key component in the total synthesis of a variety of alkaloids and pharmaceutical compounds due to its unique structure and functional groups, making it a significant molecule in organic and medicinal chemistry. It has also been investigated for its potential pharmacological activities, which include analgesic, anti-inflammatory, and anticancer properties.
2132-34-5
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Basic information
- Product Name: (4Z,6Z,8E)-Cyclohepta[b]pyrrol-2(1H)-one
- Synonyms: cycloheptapyrrol-2(1H)-one;cycloheptapyrrol-2(1H)-one
- CAS NO:2132-34-5
- Molecular Formula: C9H7NO
- Molecular Weight: 145.16
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (4Z,6Z,8E)-Cyclohepta[b]pyrrol-2(1H)-one(CAS DataBase Reference)
- NIST Chemistry Reference: (4Z,6Z,8E)-Cyclohepta[b]pyrrol-2(1H)-one(2132-34-5)
- EPA Substance Registry System: (4Z,6Z,8E)-Cyclohepta[b]pyrrol-2(1H)-one(2132-34-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 2132-34-5(Hazardous Substances Data)
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2132-34-5 Usage
Uses
Used in Pharmaceutical Synthesis:Norbelladine is used as a building block in the pharmaceutical industry for the synthesis of various alkaloids and pharmaceutical compounds. Its unique structure allows for the creation of a wide range of therapeutic agents.
Used in Organic Chemistry:
In the field of organic chemistry, norbelladine is utilized for its distinctive seven-membered ring structure containing a nitrogen atom, which makes it a valuable compound for research and development of new chemical entities.
Used in Medicinal Chemistry:
Norbelladine is employed in medicinal chemistry as a starting point for the development of new drugs, particularly those with potential analgesic, anti-inflammatory, and anticancer properties. Its pharmacological activities make it a promising candidate for further investigation and application in drug discovery.
Used in Natural Product Extraction:
Norbelladine can be extracted from certain natural products, such as Amaryllidaceae alkaloids, and used in the production of various compounds with medicinal and pharmaceutical applications.
Used in Cancer Research:
Norbelladine is used in cancer research as a potential anticancer agent. Its pharmacological properties are being studied to understand its effects on tumor growth and progression, as well as its potential synergistic effects when combined with conventional chemotherapeutic drugs.
Used in Drug Delivery Systems:
Similar to other bioactive compounds, norbelladine may benefit from novel drug delivery systems to enhance its bioavailability, delivery, and therapeutic outcomes. Researchers are exploring the use of various organic and metallic nanoparticles as carriers for norbelladine, aiming to improve its efficacy against cancer cells and other diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 2132-34-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,3 and 2 respectively; the second part has 2 digits, 3 and 4 respectively.Calculate Digit Verification of CAS Registry Number 2132-34:
(6*2)+(5*1)+(4*3)+(3*2)+(2*3)+(1*4)=45
45 % 10 = 5
So 2132-34-5 is a valid CAS Registry Number.
2132-34-5Upstream product
2132-34-5Downstream Products
- 132625-40-2 1-(2-methyl-1-phenyl-1-propyl)cycloheptapyrrol-2(1H)-one
- 132625-43-5 2-(2-Methyl-1-phenyl-propoxy)-cyclohepta[b]pyrrole
- 132625-45-7 1-Benzhydryl-1H-cyclohepta[b]pyrrol-2-one
- 132625-29-7 2-Benzhydryloxy-cyclohepta[b]pyrrole
- 106577-76-8 1-(2',3',5'-tri-O-benzoyl-α-D-arbinofuranosyl)cycloheptapyrrol-2(1H)-one
- 106577-78-0 3-(2',3',5'-tri-O-benzoyl-β-D-arbinofuranosyl)cycloheptapyrrol-2(1H)-one
- 106577-77-9 3-(2',3',5'-tri-O-benzoyl-α-D-arbinofuranosyl)cycloheptapyrrol-2(1H)-one
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(4Z,6Z,8E)-Cyclohepta[b]pyrrol-2(1H)-one
