213313-92-9Relevant academic research and scientific papers
Synthesis and biological evaluation of new tetrahydronaphthalene derivatives as thromboxane receptor antagonists
Cimetiere, Bernard,Dubuffet, Thierry,Muller, Olivier,Descombes, Jean-Jacques,Simonet, Serge,Laubie, Michel,Verbeuren, Tony J.,Lavielle, Gilbert
, p. 1375 - 1380 (2007/10/03)
New polysubstituted tetrahydronaphthalene derivatives were prepared as thromboxane receptor (TP-receptor) antagonists. Within this series of compounds S 18886 has been identified as an orally active, highly potent antagonist with a very long duration of action in different species.
