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5-((4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)methyl)thiazolidine-2,4-dione is a complex organic compound with a unique molecular structure. It belongs to the thiazolidinedione class of compounds and has potential applications in various fields due to its specific properties.
Used in Pharmaceutical Industry:
5-((4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)methyl)thiazolidine-2,4-dione is used as a PPARγ agonist for the treatment of Type 2 diabetes. It activates peroxisome proliferator-activated receptor γ (PPARγ), which plays a crucial role in regulating glucose homeostasis and insulin sensitivity. 5-((4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)methyl)thiazolidine-2,4-dione has demonstrated the ability to increase [3H]2-deoxyglucose transport and glycogen synthesis in muscle strips isolated from obese rats, indicating its potential as an anti-diabetic agent.
Used in Drug Metabolism Studies:
5-((4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)methyl)thiazolidine-2,4-dione is also a cytochrome P 450 2C19 (CYP2C19) substrate. This property makes it useful in studying the role of CYP2C19 in drug metabolism and its potential interactions with other medications. Understanding these interactions can help in optimizing drug therapy and minimizing adverse effects.

213411-83-7

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213411-83-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 213411-83-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,3,4,1 and 1 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 213411-83:
(8*2)+(7*1)+(6*3)+(5*4)+(4*1)+(3*1)+(2*8)+(1*3)=87
87 % 10 = 7
So 213411-83-7 is a valid CAS Registry Number.
InChI:InChI=1/C24H20N2O4S2/c1-14-18(25-23(30-14)15-5-3-2-4-6-15)9-11-29-19-8-7-16(21-17(19)10-12-31-21)13-20-22(27)26-24(28)32-20/h2-8,10,12,20H,9,11,13H2,1H3,(H,26,27,28)

213411-83-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-[[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl]methyl]-1,3-thiazolidine-2,4-dione

1.2 Other means of identification

Product number -
Other names UNII-8GKF7V499B

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:213411-83-7 SDS

213411-83-7Downstream Products

213411-83-7Relevant academic research and scientific papers

Novel process for the preparation of the insulin sensitizer

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Page 8, (2010/02/10)

A novel process for the preparation of compounds of formula I and optionally converting a compound of formula I into a pharmaceutically acceptable salt is disclosed. The compounds of formula I and the corresponding salts, e.g. the sodium salts, are pharma

Process for the preparation of thiazolidinedione derivatives

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, (2008/06/13)

The present invention is concerned with a novel process for the preparation of compounds of formula I comprising bromomethylation or chloromethylation of a compound of formula II and subsequent reaction with a compound of formula IV The compounds of formu

Thiazolidinediones and drugs containing them

-

, (2008/06/13)

Compounds of formula I STR1 in which A denotes a carbocyclic ring with 5 or 6 carbon atoms or a heterocyclic ring with a maximum of 4 heteroatoms in which the heteroatoms can be the same or different and denote oxygen, nitrogen or sulphur and the heterocy

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