21351-31-5

Basic information

• Product Name: N-tert-butylethanethioamide
• Synonyms: N-tert-butylethanethioamide
• CAS NO: 21351-31-5
• Molecular Weight: 131.242
• Mol File: 21351-31-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-tert-butylethanethioamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-butylethanethioamide(21351-31-5)
• EPA Substance Registry System: N-tert-butylethanethioamide(21351-31-5)

Safety Data

• Hazardous Substances Data: 21351-31-5(Hazardous Substances Data)

Upstream product

• 19172-47-5 Lawessons reagent 
• 51338-95-5 N-hydroxy-N-(1,1-dimethylethyl)ethanamide 
• 762-84-5 N-tert-butylacetamide 

Downstream Products

• 62-55-5 thioacetamide 

Relevant articles and documents

Lawesson's reagent for direct thionation of hydroxamic acids: Substituent effects on LR reactivity

To explore the generality and scope of direct thionation of hydroxamic acids (HAs), the reaction of various structurally diverse HAs with Lawesson's reagent was investigated. The yield of thiohydroxamic acid (THAs) is poor when HAs possess bulky acyl and/or N-substituents, acidic α-hydrogen atoms, or an N-phenyl ring. THAs yields were correlated with Brown sigma parameter. The relative rates of two subsequent processes kT2 and kR2 were also measured. Correlation was also found for methine proton chemical shifts of N-isopropyl benzothiohydroxamic acids.