213692-98-9Relevant academic research and scientific papers
Asymmetric synthesis of (S)-vigabatrin and (S)-dihydrokavain via cobalt catalyzed hydrolytic kinetic resolution of epoxides
Paul Raj, I. Victor,Sudalai
, p. 2646 - 2648 (2008/09/19)
A concise route to the asymmetric synthesis of (S)-vigabatrin and (S)-dihydrokavain has been described using Co-catalyzed hydrolytic kinetic resolution of racemic epoxides and regiospecific opening of terminal epoxides with dimethylsulfonium me
Asymmetric synthesis of anti-convulsive drug (S)-Vigabatrin
Chandrasekhar,Mohapatra, Suchismita
, p. 6415 - 6418 (2007/10/03)
An asymmetric synthesis of fully protected (S)-Vigabatrin is described using Sharpless asymmetric aminohydroxylation and reductive elimination of α-oxyβ-amino carbonylhydrazone as key steps.
