213698-08-9

Upstream product

• 213698-01-2 C₃₂H₄₂N₃O₆P 
• 213698-03-4 C₃₂H₄₀N₃O₆P 
• 213698-00-1 N,N'-diisobutyl-diamidophosphoryl chloride 
• 6306-52-1 L-valine methylester hydrochloride 
• 213698-13-6 C₃₈H₃₉F₅N₃O₆P 

Relevant academic research and scientific papers

N,N′-Dialkyldiamide-Type Phosphate Protecting Groups for Fmoc Synthesis of Phosphotyrosine-Containing Peptides: Optimization of the Alkyl Group

Synthesis and evaluation of three Fmoc-phosphotyrosine derivatives with a phosphate group protected as N,N'dialkyldiamide (alkyl = Prn, Pri, and Bui) were studied. All the derivatives were obtained as crystals, among which the Bu' derivative (4c) was the best in ease of preparation and excellence in cleavage property. Solid phase synthesis of a methionine-containing peptide, H-TVr(PO3H2)-Val-Pro-Met-Leu-OH, could be done without any problems.