213698-57-8Relevant academic research and scientific papers
A versatile synthesis of fully aromatic benzo[c]phenanthridine alkaloids
Geen, Graham R.,Mann, Inderjit S.,Mullane, M. Valerie,McKillop, Alexander
, p. 9875 - 9894 (1998)
A versatile new approach for the synthesis of benzo[c]phenanthridine alkaloids is described and is illustrated by the preparation of eight different alkaloids. The key steps are Smiles rearrangements, which allow easy access to 2-bromo-1-naphthylamines from 2-bromo-1-naphthols, and the attachment of the D-ring unit by Suzuki coupling.
