213738-99-9Relevant academic research and scientific papers
4-(2,2-Dimethyldioxalan-4-yl)-5-(pterin-6-yl)-1,3-dithiol-2-ones proligands relating to the cofactor of the oxomolybdoenzymes
Dinsmore, Andrew,Garner, C. David,Joule, John A.
, p. 9559 - 9568 (1998)
The coupling of the 6-iodopterins 11e and 12d to 4-(2,2-dimethyl-1,3- dioxolan-4-yl)-5-(tributylstannyl)-1,3-dithiol-2-one 8 gave 4-(2-(N,N- dimethylaminomethyleneamino)-3-(2,2-dimethylpropanoyloxymethyl)pteridin-4- on-6-y1)-5-(2,2-dimethyl-1,3-dioxolan-4
Preparation of 6-ethynylpteridine derivatives by Sonogashira coupling
Nxumalo, Winston,Dinsmore, Andrew
, p. 79 - 89 (2013/03/14)
Sonogashira coupling of 6-sulfonyloxypteridine with various acetylenes is reported. Hydrolysis of the protecting groups with 1M NH3 gave the 6-subustituted 2,4-diaminopteridine while hydrolysis with 1M NaOH gave the 6-subsituted pterin.
Negishi coupling of pteridine-o-sulfonates
Nxumalo, Winston,Dinsmore, Andrew
, p. 42 - 46 (2013/03/28)
Negishi coupling of pteridine-O-sulfonate with Zn-aryls is reported. Hydrolysis of the protecting groups with 1MNH3 gave the 6-subustituted 2,4-diaminopteridine while hydrolysis with 1 M NaOH gave the 6-subsituted pterin.
