213764-92-2 Usage
Chemical Properties
Colourless oil
Uses
5-IODO-A-85380 Dihydrochloride is a highly potent and subtype-selective agonist for AChR α4β2 and AChR α6β2.
Biological Activity
A highly potent and subtype-selective agonist for the α 4 β 2 and α 6 β 2 nicotinic acetylcholine receptors. Activates α -CTx-MII-sensitive and -insensitive components of [ 3 H]dopamine release from rat striatal synaptosomes, corresponding to α 6 β 2 and α 4 β 2 (EC 50 values are 12.7 and ~35 nM respectively). ~5000- , 25000- and 140000-fold selective over α 3 β 4, α 7 and muscle nAChR receptors respectively.
Check Digit Verification of cas no
The CAS Registry Mumber 213764-92-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,3,7,6 and 4 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 213764-92:
(8*2)+(7*1)+(6*3)+(5*7)+(4*6)+(3*4)+(2*9)+(1*2)=132
132 % 10 = 2
So 213764-92-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H11IN2O.2ClH/c10-7-3-9(5-11-4-7)13-6-8-1-2-12-8;;/h3-5,8,12H,1-2,6H2;2*1H/t8-;;/m0../s1