213765-18-5

Upstream product

• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 36199-02-7 3,4-di-O-benzyl-D-mannitol 
• 69-65-8 mannitol 
• 124-22-1 n-Dodecylamine 
• 172147-86-3 Methanesulfonic acid (1R,2S,3S,4R)-2,3-bis-benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-1-(tert-butyl-dimethyl-silanyloxymethyl)-4-methanesulfonyloxy-pentyl ester 
• 111476-62-1 3,4-di-O-benzyl-1,2:5,6-di-O-isopropylidene-D-mannitol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 172147-87-4 (2R,3R,4R,5R)-3,4-Bis-benzyloxy-1,6-bis-(tert-butyl-dimethyl-silanyloxy)-hexane-2,5-diol 

Downstream Products

• 213765-42-5 Carbonic acid bis-[(2R,3S,4S,5R)-3,4-bis-benzyloxy-5-(tert-butyl-dimethyl-silanyloxymethyl)-1-dodecyl-pyrrolidin-2-ylmethyl] ester 
• 213765-39-0 [(2R,3S,4S,5R)-3,4-Bis-benzyloxy-5-(tert-butyl-dimethyl-silanyloxymethyl)-1-dodecyl-pyrrolidin-2-yl]-methanol 

Relevant academic research and scientific papers

Synthesis of amphiphilic polyhydroxylated pyrrolidines as potential glycosidase inhibitors

Several polyhydroxylated pyrrolidines with an aliphatic long chain on the ring nitrogen were prepared starting from D-mannitol. An amphiphilic bis- azasugar scaffold has been also prepared. These products behave as cationic surfactants and show a promising anti HIV-1 activity.