213913-84-9

Upstream product

• 108-39-4 3-methyl-phenol 
• 14869-02-4 R-(E)-1-(benzyloxy)pent-3-en-2-ol 
• 213913-83-8 Toluene-4-sulfonic acid (S)-2-(2-methoxymethoxy-4-methyl-phenyl)-6-methyl-hept-5-enyl ester 
• 213913-76-9 (S)-9-[3-(1-Methoxy-1-methyl-ethoxy)-propyl]-3,6,6-trimethyl-8,9-dihydro-5,7-dioxa-benzocycloheptene 
• 213913-79-2 3-((S)-3,6,6-Trimethyl-8,9-dihydro-5,7-dioxa-benzocyclohepten-9-yl)-propionaldehyde 
• 213913-78-1 3-((S)-3,6,6-Trimethyl-8,9-dihydro-5,7-dioxa-benzocyclohepten-9-yl)-propan-1-ol 
• 213913-81-6 2-((S)-1-Hydroxymethyl-5-methyl-hex-4-enyl)-5-methyl-phenol 
• 213913-75-8 (S)-2-(2-Hydroxy-4-methyl-phenyl)-pentane-1,5-diol 
• 213913-80-5 (S)-3,6,6-Trimethyl-9-(4-methyl-pent-3-enyl)-8,9-dihydro-5,7-dioxa-benzocycloheptene 
• 213913-82-7 (S)-2-(2-Methoxymethoxy-4-methyl-phenyl)-6-methyl-hept-5-en-1-ol 

Downstream Products

• 70878-71-6 (S)-curcuphenol 

Relevant academic research and scientific papers

Efficient enantioselective total synthesis of (+)-helianane

The enantiocontrolled total synthesis of (+)-helianane, a marine-derived heterocyclic sesquiterpene, has been accomplished with an efficient chirality transfer during the Me3Al-mediated aromatic Claisen rearrangement and a ring-closing metathesis as the key steps. The absolute structure of the natural product has been firmly established by total synthesis. Georg Thieme Verlag Stuttgart - New York.

A new stereocontrolled route to (+)-curcuphenol, a phenolic sesquiterpene from the marine sponge Didiscus flavus

Using a synthetic equivalent of chiral 2-cyclopentenol, (+)- curcuphenol, a cytotoxic bisabolane type sesquiterpene isolated from the marine sponge Didiscus flavus, has been synthesized through a concurrent retro-Diels-Alder reaction and Claisen rearrange