21394-57-0

Basic information

• Product Name: N-Myristoyl-L-serine
• Synonyms: N-myristoyl-L-serine;2-(Tetradecanoylamino)-3-hydroxypropanoic acid;N-(1-Oxotetradecyl)-L-serine;N-Tetradecanoyl-L-serine;Einecs 244-363-5;N-TETRADECANOYL-SERINE
• CAS NO: 21394-57-0
• Molecular Formula: C17H33NO4
• Molecular Weight: 315.45
• EINECS: 244-363-5
• Mol File: 21394-57-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 519.793 °C at 760 mmHg
• Flash Point: 268.162 °C
• Appearance: /
• Density: 1.025 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.481
• CAS DataBase Reference: N-Myristoyl-L-serine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Myristoyl-L-serine(21394-57-0)
• EPA Substance Registry System: N-Myristoyl-L-serine(21394-57-0)

Safety Data

• Hazardous Substances Data: 21394-57-0(Hazardous Substances Data)

Usage

General Description

N-Myristoyl-L-serine is a chemical compound with the molecular formula C18H35NO3. It is a synthetic derivative of the amino acid serine, where myristoyl group is attached to the amino group of serine. N-Myristoyl-L-serine is used in research as a tool for studying protein lipidation, which is a process of attaching lipid chains to proteins. N-Myristoyl-L-serine is also used in studies related to protein-protein interactions and membrane targeting. It is a potentially important compound for investigating cellular signaling pathways and functions involving myristoylated proteins. Additionally, it has potential applications in drug development and biochemical research.

InChI:InChI=1/C17H33NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-16(20)18-15(14-19)17(21)22/h15,19H,2-14H2,1H3,(H,18,20)(H,21,22)/t15-/m0/s1

Upstream product

• 544-63-8 n-tetradecanoic acid 
• 56-45-1 L-serin 
• 112-64-1 tetradecanoyl chloride 
• 302-84-1 serin 

Relevant articles and documents

The relationship between the structure and properties of amino acid surfactants based on glycine and serine

Two series of surfactants based on glycine and serine were synthesized with aproic acid, octanoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid and hexadecanoic acid. All the surfactants were characterized by MS and 1H NMR, the structures of the synthesized surfactants are correct and the signals in MS and 1H NMR can be explained. The reaction conditions, surface properties and foam properties were studied. For the two series of surfactants, critical micelle concentration (CMC) and γ CMC (surface tension at CMC) decrease and surface activity is enhanced as the length of carbon chain increases. The surfactants with tetradecanoyl and hexadecanoyl groups show a good foaming property and especially, the long-chain acyl-serine performs better. These are all related to the hydromethyl group in the serine.

Antipsychotic drug

The present invention provides an antipsychotic drug containing essentially an N-acyl amino acid derivative represented by the following general formula:RCO-Awherein R indicates an alkyl or alkenyl having 1-25 carbon atoms, and A is an amino acid residue. The compound is similar to natural products and has little side effect by acting directly to brain cells after passing through easily the blood brain barrier.