213978-36-0Relevant academic research and scientific papers
Process for the preparation of a 2-oxopyrrolidine compound
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, (2008/06/13)
A process for producing a lactam of the formula STR1 wherein 2-bromo-4 chloro butyryl bromide or 2,4-dibromo butyryl bromide is coupled with 4-aminobenzonitrile to produce 4-(2,4-bromobutyrylamino)-benzonitrile, which is combined with sodium hydroxide, po
An efficient asymmetric synthesis of (3S)-3-amino-1-(4-cyanophenyl)-2- oxopyrrolidine hydrochloride salt
Colson, Pierre-Jean,Przybyla, Claire A.,Wise, Bruce E.,Babiak, Kevin A.,Seaney, Lisa M.,Korte, Donald E.
, p. 2587 - 2593 (2007/10/03)
Reaction of 4-aminobenzonitrile with 2-bromo-4-chlorobutyryl bromide in the presence of sodium phosphate followed by treatment of the coupled product with sodium hydroxide followed by ammonium hydroxide in acetonitrile yielded the title compound as the ra
