213988-08-0

Upstream product

• 213988-07-9 8-(6-Methoxy-2-propyloxy-3-nitrobenzyloxy)-2-methylquinoline 
• 213988-06-8 6-Methoxy-2-propyloxy-3-nitrobenzyl bromide 

Relevant academic research and scientific papers

Benzyloxy-substituted, fused N-heterocycles, processes for their preparation, and their use as bradykinin receptor antagonists

Benzyloxy-substituted, fused N-heterocycles, because of their ability to act as bradykinin receptor antagonists, have been found to be useful as therapeutics for the treatment and prevention of liver cirrhosis or Alzheimer''s disease. This application describes such compounds, as well as processes for their preparation and use. The compounds according to this invention include compounds of formula (I) STR1in which B, D, R 1, and R 2 have the meanings indicated herein.

Novel series of O-substituted 8-quinolines and 4-benzothiazoles as potent antagonists of the bradykinin B2 receptors

The synthesis and the SAR study of novel O-substituted 8-quinolines and 4-benzothiazoles as highly potent non-peptide bradykinin B2 receptor antagonists are described. Several members of this series of antagonists efficiently inhibited the BK-induced vasoconstriction on different isolated organ preparations.