213993-30-7

Basic information

• Product Name: Cyclohexanemethanol, 2-amino-, (1S,2R)- (9CI)
• Synonyms: Cyclohexanemethanol, 2-amino-, (1S,2R)- (9CI);((1S,2R)-2-aMinocyclohexyl)Methanol;CyclohexaneMethanol, 2-aMino-, (1S,2R)-
• CAS NO: 213993-30-7
• Molecular Formula: C₇H₁₅NO
• Molecular Weight: 129.2001
• Product Categories: AMINEPRIMARY
• Mol File: 213993-30-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclohexanemethanol, 2-amino-, (1S,2R)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanemethanol, 2-amino-, (1S,2R)- (9CI)(213993-30-7)
• EPA Substance Registry System: Cyclohexanemethanol, 2-amino-, (1S,2R)- (9CI)(213993-30-7)

Safety Data

• Hazardous Substances Data: 213993-30-7(Hazardous Substances Data)

Upstream product

• 179601-38-8 (1S,2R)-2-aminocyclohexanecarboxylic acid ethyl ester 
• 189101-41-5 (1S,2R)-(+)-2-aminocyclohexane-1-carboxylic acid 

Downstream Products

• 1266398-73-5 ((1S,2R)-2-(benzo[d]thiazol-2-ylamino)cyclohexyl)methanol 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AND USE THEREOF AS MODULATORS OF TYPE III RECEPTOR TYROSINE KINASES

Provided herein are heterocyclic compounds for treatment of CSF1R, FLT3, KIT, and/or PDGFRβ kinase mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions.

Structure-enantioselectivity effects in 3,4-dihydropyrimido[2,1-b] benzothiazole-based isothioureas as enantioselective acylation catalysts

The catalytic activity and enantioselectivity in the kinetic resolution of (±)-1-naphthylethanol with a range of structurally related 3,4-dihydropyrimido[2,1-b]benzothiazole-based catalysts is examined. Of the isothiourea catalysts screened, (2S,3R)-2-phenyl-3-isopropyl substitution proved optimal, giving good levels of selectivity in the kinetic resolution of a number of secondary alcohols (S values up to >100 at ～50% conversion). Low catalyst loadings (0.10-0.25 mol%) of the optimal isothiourea can be used to generate enantiopure alcohols (>99% ee) in good yields.