214001-03-3Relevant articles and documents
Design, synthesis, and characterization of novel iron chelators: Structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents
Kalinowski, Danuta S.,Yu, Yu,Sharpe, Philip C.,Islam, Mohammad,Liao, Yi-Tyng,Lovejoy, David B.,Kumar, Naresh,Bernhardt, Paul V.,Richardson, Des R.
, p. 3716 - 3729 (2007)
Previously, we demonstrated that the potent antiproliferative activity of the di-2-pyridylketone thiosemicarbazone (DpT) series of Fe chelators was due to their ability to induce Fe depletion and form redox-active Fe complexes (Richardson, D. R.; et al. J
Chemoselective homogeneous hydrogenation of phenylacetylene using thiosemicarbazone and thiobenzoylhydrazone palladium(II) complexes as catalysts
Pelagatti, Paolo,Venturini, Andrea,Leporati, Andrea,Carcelli, Mauro,Costa, Mirco,Bacchi, Alessia,Pelizzi, Giancarlo,Pelizzi, Corrado
, p. 2715 - 2721 (2007/10/03)
A series of monometallic palladium(II) complexes with thiosemicarbazones and thiobenzoylhydrazones has been synthesized and characterised by spectroscopic methods. The crystal structures of chloro(phenyl 2-pyridyl ketone thiosemicarbazonato)palladium(II) 1a and chloro(phenyl 2-pyridyl ketone thiobenzoylhydrazonato)palladium(II) 2 were also determined. The catalytic activity of the complexes in the homogeneous hydrogenation of phenylacetylene was tested with particular regard to the chemoselectivity from a triple to a double bond. Using chlorocomplexes a high chemoselectivity was always observed. Results of a kinetic study of the hydrogenation of phenylacetylene in the presence of chloro(methyl 2-pyridyl ketone thiosemicarbazonato)palladium(II) 3 as catalyst provided suggestions for the elucidation of the catalytic cycle of the reaction.
