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214047-00-4

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Product FOB Price Min.Order Supply Ability Supplier
Palmitoyl pentapeptide-4
Cas No: 214047-00-4
No Data 1 Gram 10 Kilogram/Month HANGZHOU CLAP TECHNOLOGY CO,.LTD Contact Supplier
Palmitoyl pentapeptide-4/3,Matrixyl Acetate high-quality Sufficient supply
Cas No: 214047-00-4
No Data No Data Metric Ton/Day Sichuan Jisheng BioPharmaceutical Co., Ltd. Contact Supplier
skin care peptide Palmitoyl Pentapeptide-4 for cosmetic products
Cas No: 214047-00-4
USD $ 1.0-1.0 / Kilogram 1 Kilogram 1000 Kilogram/Month Guangzhou Trojan Pharmatech Ltd Contact Supplier
Matrixyl
Cas No: 214047-00-4
No Data 1 Gram 10 Kilogram/Month Shenzhen JYMed Technology Co.,Ltd. Contact Supplier
Matrixyl in stock
Cas No: 214047-00-4
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-10 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
Palmitoyl pentapeptide
Cas No: 214047-00-4
No Data 1 Kilogram 30 Metric Ton/Month Simagchem Corporation Contact Supplier
High purity 214047-00-4 Palmitoyl pentapeptide
Cas No: 214047-00-4
USD $ 100.0-500.0 / Gram 1 Gram 99999 Gram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
Matrixyl 3000/N2-(1-Oxohexadecyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-L-serine
Cas No: 214047-00-4
No Data 1 Gram 1 Metric Ton/Month Kono Chem Co.,Ltd Contact Supplier
Cosmetic peptide Palmitoyl pentapeptide Cas 214047-00-4 with high quality and competitive price
Cas No: 214047-00-4
USD $ 60.0-68.0 / Gram 1 Gram 5 Kilogram/Month Wuhan Fortuna Chemical Co.,Ltd Contact Supplier
Palmitoyl Pentapeptide-4 manufacturer with low price
Cas No: 214047-00-4
No Data 1 Gram 1000 Metric Ton/Month Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd Contact Supplier

214047-00-4 Usage

Uses

anti-wrikle

Application and Synthesis method

Cosmetic polypeptides can penetrate the dermis to increase the level of collagen and reverse the aging process of the skin through rebuilding from inside to outside.
Cosmetic pentapeptide is also a cosmetic polypeptide. The prototype of the polypeptide is palmitic acid pentapeptide, commonly known as the five peptides, being able to simulate the paralysis effect of botulinum toxin. It is a short peptide fragment consisting of five amino acids formed by peptide bonds with its structure being similar to the protein. However, the protein has a longer peptide chain, usually consisting of hundreds of amino acids. Based on the differences of the number of amino acids, these polypeptides are divided into dipeptides (including two amino acids), tripeptides (including three amino acids), tetrapeptides (including four amino acids), etc. Because of the different categories of amino acids contained, both dipeptides and tripeptides have different varieties. At the same time, even with the same number of amino acids, the dipeptides will still have different varieties due to the different sort order of the amino acid. This leads to a number of peptides with a variety of roles and names. The pentapeptide is composed of six amino acids (Pal palmitic acid, Lys-lysine, Thr-threonine, Thr-threonine, Lys-lysine and Ser-serine).
The cosmetic pentapeptide is actually the C-terminal fragment of Collagen I, having an effect being similar to that of the laser surgery. It can stimulate the growth of collagen, stretch fibers and hyaluronic acid, improve skin moisture and the degree of locking water, increase skin thickness and reduce the microgroove; at the same time, addition of a long chain of fatty acids (palmitic acid) can increase the absorption effect. Compared with the laser surgery, the five-peptides is equivalent to intimate fusion with the skin, changing the skin ecology and cell repair, further playing the role of intracellular hormones and enzymes.
InChI:InChI=1/C39H75N7O10/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-23-32(50)42-29(21-17-19-24-40)36(52)45-34(28(3)49)38(54)46-33(27(2)48)37(53)43-30(22-18-20-25-41)35(51)44-31(26-47)39(55)56/h27-31,33-34,47-49H,4-26,40-41H2,1-3H3,(H,42,50)(H,43,53)(H,44,51)(H,45,52)(H,46,54)(H,55,56)/t27?,28?,29-,30-,31-,33-,34-/m0/s1

214047-00-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name L-Serine, N2-(1-oxohexadecyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-

1.2 Other means of identification

Product number -
Other names palmitoyl pentapeptide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:214047-00-4 SDS

214047-00-4Synthetic route

Fmoc-Ser(tBu)-OH
71989-33-8

Fmoc-Ser(tBu)-OH

Fmoc-Lys(tert-butoxycarbonyl)
71989-26-9

Fmoc-Lys(tert-butoxycarbonyl)

Fmoc-Thr-OH
73731-37-0

Fmoc-Thr-OH

Fmoc-Lys-OH
105047-45-8

Fmoc-Lys-OH

1-hexadecylcarboxylic acid
57-10-3

1-hexadecylcarboxylic acid

palmitoyl-lysine-threonine-threonine-lysine-serine
214047-00-4

palmitoyl-lysine-threonine-threonine-lysine-serine

Conditions
ConditionsYield
Stage #1: Fmoc-Ser(tBu)-OH With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide for 6h;
Stage #2: With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide
Stage #3: Fmoc-Lys(tert-butoxycarbonyl); Fmoc-Thr-OH; Fmoc-Lys-OH; 1-hexadecylcarboxylic acid Further stages;
24.9%

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