214057-97-3Relevant academic research and scientific papers
Synthesis of spiroisoxazolines via TEMPO/NaNO2-catalyzed aerobic oxidative dearomatization
Chen, Dengfeng,Wang, Yaming,Cai, Xu-Min,Cao, Xiaoji,Jiang, Ping,Wang, Fei,Huang, Shenlin
, p. 6847 - 6851 (2020)
A catalytic, aerobic oxidative dearomatization protocol has been developed for the preparation of spiroisoxazline scaffolds from oximes using TEMPO and NaNO2 as the catalyst and O2 as the sole oxidant. This dearomatization methodology features its mild reaction conditions, good functional group tolerance, and an unprecedented broad substrate scope, encompassing phenols, aryl ethers, thiophenols, aryl sulfides, etc.
Approaches to the synthesis of some tyrosine-derived marine sponge metabolites: Synthesis of verongamine and purealidin N
Boehlow,Harburn,Spilling
, p. 3111 - 3118 (2007/10/03)
The oxidation of tyrosine ethyl ester (7) with Na2WO4/H2O2 in ethanol, dimethyldioxirane in acetone, or methyltrioxorhenium/H2O2 in EtOH gave the corresponding tyrosine oxime (8) in high yi
