214117-54-1

Basic information

• Product Name: 4-(4-Bromo-phenyl)-2-((S)-sec-butyl)-2,4-dihydro-[1,2,4]triazol-3-one
• CAS NO: 214117-54-1
• Molecular Weight: 296.167
• Mol File: 214117-54-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-Bromo-phenyl)-2-((S)-sec-butyl)-2,4-dihydro-[1,2,4]triazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Bromo-phenyl)-2-((S)-sec-butyl)-2,4-dihydro-[1,2,4]triazol-3-one(214117-54-1)
• EPA Substance Registry System: 4-(4-Bromo-phenyl)-2-((S)-sec-butyl)-2,4-dihydro-[1,2,4]triazol-3-one(214117-54-1)

Safety Data

• Hazardous Substances Data: 214117-54-1(Hazardous Substances Data)

Upstream product

• 2493-02-9 4-bromophenyl isocyanate 
• 890342-21-9 C₈H₈BrN₃O₂ 
• 61530-30-1 (R)-sec-butyl 4-methylbenzenesulfonate 
• 214117-50-7 2,4-dihydro-4-(4-bromophenyl)-3H-1,2,4-triazol-3-one 

Downstream Products

• 153896-47-0 (S)-2-(sec-butyl)-4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 

Relevant articles and documents

Pd-catalyzed aminations of aryl triazolones: Effective synthesis of hydroxyitraconazole enantiomers

A palladium-catalyzed amination of triazolone 3 by piperazine 2 was used as the key step in an efficient synthesis of highly enantiomerically-pure hydroxyitraconazole isomers. Compound 2 (>99%ee) was prepared by reaction of an achiral phenol precursor wit