214139-75-0Relevant academic research and scientific papers
Antiviral protease inhibitors
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, (2008/06/13)
Compounds of the formula I: wherein: A′ and A″ are independently the same or different group of the formula II: wherein: R′ is H. CH3, C(CH3)2, —ORa, —N(Ra)2, —N(Ra)ORa/sup
Design and synthesis of potent C2-symmetric diol-based HIV-1 protease inhibitors: Effects of fluoro substitution
Pyring,Lindberg,Rosenquist,Zuccarello,Kvarnstr?m,Zhang,Vrang,Unge,Classon,Hallberg,Samuelsson
, p. 3083 - 3091 (2007/10/03)
Implementation of derivatized carbohydrates as C2-symmetric HIV-1 protease inhibitors has previously been reported. With the objective of improving the anti-HIV activity of such compounds, we synthesized a series of fluoro substituted P1/P1′ an
