214222-19-2Relevant academic research and scientific papers
Palladium-catalyzed cyclization of silyl-substituted bis(homo)propargylic alcohols to 2,3-dihydrofurans
Schabbert, Silke,Schaumann, Ernst
, p. 1873 - 1878 (2007/10/03)
Ring-opening of oxiranes 1 by the silicon- and sulfur-functionalized propargyl anions 2 yields the corresponding alk-4-yn-1-ols 3. Cyclization of 3 to 2,3-dihydro-4-phenylthiofurans 5 is achieved by reaction with palladium(II) acetate. The corresponding f
