214285-87-7Relevant academic research and scientific papers
Amine alkylation reaction continuous flow process
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Paragraph 0018; 0032-0035, (2021/02/24)
The invention relates to an amine alkylation reaction continuous flow process, in particular to a method for preparing an alkoxy amine acetone compound through the amine alkylation reaction continuousflow process. A raw material alkoxy aniline organic sol
Preparation method of 4-AA key intermediate epoxy butylamide
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Paragraph 0016; 0018, (2019/11/12)
The invention relates to a preparation method of 4-AA key intermediate epoxy butylamide. The preparation method comprises the steps that (1) synthesis of epoxy butyric acid is conducted: a starting material L-threonine is cyclized under diazotization and
Preparation method of N-acetonyl amine compound
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Paragraph 0046, (2016/10/09)
The invention discloses a preparation method of an N-acetonyl amine compound. The method comprises the following steps that an amine compound and glycerin are used as reaction raw materials, and in the presence of a composite catalyst and an alkali addition agent, in reaction mediums and at the reaction temperature of 80-180 DEG C, a reaction is performed for 2-48 hours in a sealed reactor so that the N-acetonyl amine compound is obtained. The method disclosed by the invention is simple, reaction conditions are mild, target products can be obtained at a low cost and at a high yield, and the used catalyst has high catalytic activity and is easy to separate and repeatedly use in a reaction system; besides, the whole process is environment-friendly, and the utilization of by-products namely the glycerin of biologic diesel oil is promoted.
Diastereoselective cobalt-catalyzed reductive aldol cyclizations using diethylzinc as the stoichiometric reductant
Lam, Hon Wai,Joensuu, Pekka M.,Murray, Gordon J.,Fordyce, Euan A. F.,Prieto, Oscar,Luebbers, Thomas
, p. 3729 - 3732 (2007/10/03)
Cobalt catalysis enables a new method for the generation of zinc enolates using diethylzinc to reduce α,β-unsaturated amides. This method has been applied to a high-yielding diastereoselective reductive aldol cyclization.
