214344-42-0

Basic information

• Product Name: (R)-2-[(2S,3S)-3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-hydroxysulfanyl-4-oxo-azetidin-1-yl]-3-methyl-but-3-enoic acid benzyl ester
• Synonyms: (R)-2-[(2S,3S)-3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-hydroxysulfanyl-4-oxo-azetidin-1-yl]-3-methyl-but-3-enoic acid benzyl ester
• CAS NO: 214344-42-0
• Molecular Weight: 452.488
• Mol File: 214344-42-0.mol

Chemical Properties

• CAS DataBase Reference: (R)-2-[(2S,3S)-3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-hydroxysulfanyl-4-oxo-azetidin-1-yl]-3-methyl-but-3-enoic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-[(2S,3S)-3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-hydroxysulfanyl-4-oxo-azetidin-1-yl]-3-methyl-but-3-enoic acid benzyl ester(214344-42-0)
• EPA Substance Registry System: (R)-2-[(2S,3S)-3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-hydroxysulfanyl-4-oxo-azetidin-1-yl]-3-methyl-but-3-enoic acid benzyl ester(214344-42-0)

Safety Data

• Hazardous Substances Data: 214344-42-0(Hazardous Substances Data)

Upstream product

• 182268-27-5 benzyl (-)-(2S,4S,5S,6S)-3,3-dimethyl-7-oxo-6-phthalimido-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate-4-oxide 

Downstream Products

• 182186-35-2 (6S,7S)-benzyl 7-(1,3-dioxoisoindolin-2-yl)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 

Relevant articles and documents

Unusually stable azetidinone sulfenic acids

Sulfoxides of (2S,5S,6S)-penams rearrange upon heating in benzene or toluene to form unusually stable azetidinone sulfenic acids. A reversal of the process, the annelation of the sulfenic acids, is disfavoured due to steric congestion on the endo-face of the corresponding penam sulfoxides.