214346-13-1

Basic information

• Product Name: GEMIFLOXACIN MESYLATE
• Synonyms: GEMIFLOXACIN MESYLATE;1,8-Naphthyridine-3-carboxylic acid, 7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, monomethanesulfonate;Factive;Unii-X4S9F8rl01
• CAS NO: 214346-13-1
• Molecular Formula: C19H24FN5O7S
• Molecular Weight: 485.4865632
• Mol File: 214346-13-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 638.9°C at 760 mmHg
• Flash Point: 340.2°C
• Appearance: /
• Vapor Pressure: 3.36E-17mmHg at 25°C
• CAS DataBase Reference: GEMIFLOXACIN MESYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: GEMIFLOXACIN MESYLATE(214346-13-1)
• EPA Substance Registry System: GEMIFLOXACIN MESYLATE(214346-13-1)

Safety Data

• Hazardous Substances Data: 214346-13-1(Hazardous Substances Data)

Usage

Uses

Antibacterial.

InChI:InChI=1/C18H20FN5O4.C2H6O2S/c1-28-22-14-8-23(6-9(14)5-20)17-13(19)4-11-15(25)12(18(26)27)7-24(10-2-3-10)16(11)21-17;1-5(2,3)4/h4,7,9-10H,2-3,5-6,8,20H2,1H3,(H,26,27);1H2,2H3,(H,3,4)/b22-14+;

Upstream product

• 75-75-2 methanesulfonic acid 
• 175463-14-6 gemifloxacin 
• 329322-84-1 7-(3-aminomethyl-4-methoxyimino-pyrrolidine-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]-naphthyridine-3-carboxylic acid 

Relevant articles and documents

NOVEL POLYMORPHS OF GEMIFLOXACIN MESYLATE

The present invention provides novel crystalline sesquihydrate form 1, sesquihydrate form 2, anhydrous form 3 and anhydrous form 4 of gemifloxacin mesylate, processes for their preparation and pharmaceutical compositions containing them. The present inven

PROCESS FOR PRODUCTION OF NAPHTHYRIDINE-3-CARBOXYLIC ACID DERIVATIVES

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NEW PROCESS FOR PREPARING 4-AMINOMETHYL-3-ALKOXYIMINOPYRROLIDINE METHANESULFONATE

The present invention relates to a process for the preparation of 4-aminomethyl-3-alkoxyiminopyrrolidine methanesulfonate, a key intermediate of quinolone antibiotics. According to the process of the present invention, the total number of steps has been shortened to 2-3 steps, the solid separation is not required, and the use of costly chemicals, particularly (BOC)2O (t-butoxycarbonyl anhydride), several organic solvents and reactants, is eliminated.