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(3-PHTHALIMIDOMETHYLPHENYL)BORONIC ACID PINACOL ESTER, with the molecular formula C14H17BO4N1O2, is a boronic acid derivative that plays a significant role in organic synthesis and medicinal chemistry. Known for its capacity to form stable complexes with diols, (3-PHTHALIMIDOMETHYLPHENYL)BORONIC ACID PINACOL ESTER is a versatile building block in a range of chemical reactions, including the widely used Suzuki-Miyaura cross-coupling reactions. Its pinacol ester functionality further enhances its utility in the synthesis of biologically active compounds, such as pharmaceuticals and agrochemicals. Moreover, it has been explored for its potential in the development of innovative materials and catalysts.

214360-75-5

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214360-75-5 Usage

Uses

Used in Organic Synthesis:
(3-PHTHALIMIDOMETHYLPHENYL)BORONIC ACID PINACOL ESTER is used as a reagent for forming stable complexes with diols, facilitating various chemical reactions in the field of organic synthesis.
Used in Medicinal Chemistry:
In the pharmaceutical industry, (3-PHTHALIMIDOMETHYLPHENYL)BORONIC ACID PINACOL ESTER is used as a building block in the synthesis of biologically active compounds, contributing to the development of new pharmaceuticals.
Used in Suzuki-Miyaura Cross-Coupling Reactions:
(3-PHTHALIMIDOMETHYLPHENYL)BORONIC ACID PINACOL ESTER is utilized as a key component in Suzuki-Miyaura cross-coupling reactions, a widely employed method in organic chemistry for the formation of carbon-carbon bonds.
Used in the Synthesis of Agrochemicals:
In agrochemical research and development, (3-PHTHALIMIDOMETHYLPHENYL)BORONIC ACID PINACOL ESTER is used as a reagent for synthesizing biologically active compounds that can be applied in crop protection and pest management.
Used in Material Science:
(3-PHTHALIMIDOMETHYLPHENYL)BORONIC ACID PINACOL ESTER is used as a precursor in the development of new materials, potentially contributing to advancements in material properties and applications.
Used in Catalyst Development:
In the field of catalysis, (3-PHTHALIMIDOMETHYLPHENYL)BORONIC ACID PINACOL ESTER is investigated for its potential use in the creation of new catalysts, which could improve the efficiency and selectivity of various chemical processes.

Check Digit Verification of cas no

The CAS Registry Mumber 214360-75-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,4,3,6 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 214360-75:
(8*2)+(7*1)+(6*4)+(5*3)+(4*6)+(3*0)+(2*7)+(1*5)=105
105 % 10 = 5
So 214360-75-5 is a valid CAS Registry Number.
InChI:InChI=1/C21H22BNO4/c1-20(2)21(3,4)27-22(26-20)15-9-7-8-14(12-15)13-23-18(24)16-10-5-6-11-17(16)19(23)25/h5-12H,13H2,1-4H3

214360-75-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]isoindole-1,3-dione

1.2 Other means of identification

Product number -
Other names AMTB445

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:214360-75-5 SDS

214360-75-5Relevant academic research and scientific papers

COUMARIN-LIKE CYCLIC COMPOUND AS MEK INHIBITOR AND USE THEREOF

-

Paragraph 0146; 0147; 0149, (2020/05/30)

Disclosed are a class of coumarin-like cyclic compounds as MEK inhibitors and pharmaceutical compositions comprising the compounds, and the use of same in the preparation of a drug for treating MEK-related diseases. Particularly disclosed are compounds as shown in formula (I) and pharmaceutically acceptable salts thereof or tautomers thereof.

Synthesis of boron-containing primary amines

Chung, Sheng-Hsuan,Lin, Ting-Ju,Hu, Qian-Yu,Tsai, Chia-Hua,Pan, Po-Shen

, p. 12346 - 12367 (2013/11/06)

In this study, boron-containing primary amines were synthesized for use as building blocks in the study of peptoids. In the first step, Gabriel synthesis conditions were modified to enable the construction of seven different aminomethylphenyl boronate esters in good to excellent yields. These compounds were further utilized to build peptoid analogs via an Ugi four-component reaction (Ugi-4CR) under microwave irradiation. The prepared Ugi-4CR boronate esters were then successfully converted to the corresponding boronic acids. Finally, the peptoid structures were successfully modified by cross-coupling to aryl/heteroaryl chlorides via a palladium-mediated Suzuki coupling reaction to yield the corresponding derivatives in moderate to good yields.

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