214413-74-8Relevant academic research and scientific papers
Application of organolithium and related reagents in synthesis. Part 21. Synthetic strategies based on orthro-aromatic metallation. A concise regiospecific synthesis of arylnaphthalanes as precursors of naphthylisoquinoline alkaloids
Epsztajn, Jan,Jozwiak, Andrzej,Szczesniak, Aleksandra K.
, p. 2563 - 2567 (2007/10/03)
A novel procedure is described for synthesising regioselectively substituted biaryls such as 12. It involves converting phthalides 4, via cycloaddition of dimethyl acetylenedicarboxylate to 1-arylisobenzofurans 6, into dimethyl 1-arylnaphthalene-2,3-dicar
