214413-81-7

Upstream product

• 1027188-22-2 1-(2,4-Dimethoxy-6-methoxymethyl-phenyl)-4-methoxy-1,3-dihydro-isobenzofuran-1-ol 
• 74726-76-4 2-bromo-3,5-dimethoxybenzyl alcohol 
• 1027072-55-4 1-bromo-2,4-dimethoxy-6-methoxymethylbenzene 

Relevant academic research and scientific papers

Application of organolithium and related reagents in synthesis. Part 21. Synthetic strategies based on orthro-aromatic metallation. A concise regiospecific synthesis of arylnaphthalanes as precursors of naphthylisoquinoline alkaloids

A novel procedure is described for synthesising regioselectively substituted biaryls such as 12. It involves converting phthalides 4, via cycloaddition of dimethyl acetylenedicarboxylate to 1-arylisobenzofurans 6, into dimethyl 1-arylnaphthalene-2,3-dicar