21444-07-5Relevant academic research and scientific papers
Iron-Promoted Three-Component 2-Substituted Benzothiazole Formation via Nitroarene ortho-C-H Sulfuration with Elemental Sulfur
Xing, Qiaoyan,Ma, Yanfeng,Xie, Hao,Xiao, Fuhong,Zhang, Feng,Deng, Guo-Jun
, p. 1238 - 1246 (2019)
A three-component procedure for the preparation of 2-substituted benzothiazoles from nitroarenes, alcohols, and sulfur powder is described. The reaction showed a good functional group tolerance to provide the heterocyclic products in moderate to good yields. The sequential assembly involving nitro reduction, C-N condensation, and C-S bond formation has been realized in one pot.
