214531-78-9Relevant academic research and scientific papers
Use of 1,3-Dioxin-4-ones and Their Related Compounds in Synthesis. Part 28 . Asymmetric de Mayo Reactions Using Chiral Spirocyclic Dioxinones
Sato, Masayuki,Abe, Yoshito,Takayama, Kazuhisa,Sekiguchi, Keiko,Kaneko, Chikara,et al.
, p. 241 - 252 (2007/10/02)
The use of rigid spirocyclic dioxinones having 1-menthone as the chiral auxiliary as the enones in the photocycloaddition reactions opened novel methods for obtaining enantiomerically pure compounds, such as iridoids.Convex side preference of the sofa-conformation of these dioxinones in the photoaddition to cyclopentene increases up to 100percent by introducing either a bulky substituent or 5-hexenyl group at the 3-position to these dioxinones and, hence, highly asymmetric inter- and intramolecular de Mayo reactions have been disclosed.
