214535-14-5Relevant academic research and scientific papers
A facile method for the oxidation of nucleoside H-phosphonates to phosphates with bis(trimethylsilyl) peroxide
Kato, Toru,Hayakawa, Yoshihiro
, p. 1796 - 1798 (2007/10/03)
We have developed a convenient method for achieving the oxidation of nucleoside H-phosphonic acid monoesters and diesters with bis(trimethylsilyl) peroxide and N,O-bis(trimethylsilyl)acetamide in the presence of trimethylsilyl triflate as a catalyst.
Electrochemical removal of allylic protecting groups in nucleotide synthesis
Hayakawa, Yoshihiro,Kawai, Rie,Wakabayashi, Shigeharu,Uchiyama, Mamoru,Noyori, Ryoji
, p. 441 - 449 (2007/10/03)
Electrochemical, palladium(0)-mediated removal of allylic protecting groups of nucleosides and nucleotides is described. This method required no chromatographic treatment for isolation of the products.
