214619-66-6

Basic information

• Product Name: 2,3-Bis-(diethoxy-phosphorylmethyl)-benzoic acid
• CAS NO: 214619-66-6
• Molecular Weight: 422.352
• Mol File: 214619-66-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,3-Bis-(diethoxy-phosphorylmethyl)-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Bis-(diethoxy-phosphorylmethyl)-benzoic acid(214619-66-6)
• EPA Substance Registry System: 2,3-Bis-(diethoxy-phosphorylmethyl)-benzoic acid(214619-66-6)

Safety Data

• Hazardous Substances Data: 214619-66-6(Hazardous Substances Data)

Upstream product

• 603-79-2 2,3-dimethylbenzoic acid 
• 214619-64-4 2,3-Bis-bromomethyl-benzoic acid 
• 127168-91-6 methyl 2,3-bis(bromomethyl)benzoate 
• 214619-65-5 2,3-Bis-(diethoxy-phosphorylmethyl)-benzoic acid methyl ester 

Relevant articles and documents

Synthesis of Substrate Analogues and Inhibitors for the Phosphoglycerate Mutase Enzyme

Several substrate analogues of the title enzyme were synthesized as well as with possible irreversible inhibitors, analogues of phosphoglycolate, the cofactor for this enzyme.The main routes involved an Arbuzov type reaction on functionalized halides, a reaction significantly improved by a sonication procedure and reaction of the diethylphosphite anion on tosylates.Phosphorylated epoxides were obtained by quantitative oxidation of conjugate double bonds using DMDO.Preliminary assays indicated a promising activity in some of these compounds.Keywords: phosphonates; inhibitors; phosphoglycerate Mutase; Arbuzov; DMDO