21462-09-9

Basic information

• Product Name: bicyclo[2.2.1]heptane-2,5-diol
• Synonyms: 2,5-Norbornanediol; Bicyclo(2.2.1)heptane-2,5-diol
• CAS NO: 21462-09-9
• Molecular Formula: C₇H₁₂O₂
• Molecular Weight: 128.169
• Mol File: 21462-09-9.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 276.6°C at 760 mmHg
• Flash Point: 139°C
• Density: 1.292g/cm³
• Vapor Pressure: 0.000592mmHg at 25°C
• Refractive Index: 1.59
• CAS DataBase Reference: bicyclo[2.2.1]heptane-2,5-diol(CAS DataBase Reference)
• NIST Chemistry Reference: bicyclo[2.2.1]heptane-2,5-diol(21462-09-9)
• EPA Substance Registry System: bicyclo[2.2.1]heptane-2,5-diol(21462-09-9)

Safety Data

• Hazardous Substances Data: 21462-09-9(Hazardous Substances Data)

Upstream product

• 2890-96-2 5-norbornene-2-carbonitrile 
• 2888-90-6 5-norbornene-2-carbonitrile 
• 121-46-0 bicyclo[2.2.1]hepta-2,5-diene 
• 27943-47-1 norbornane-2,5-dione 
• 121-46-0 bicyclo[2.2.1]hepta-2,5-diene 
• 694-97-3 endo-5-norbornen-2-ol 
• 78987-90-3 (1RS,2RS,4SR,5SR,6RS)-3-oxatricyclo<3.2.1.0^2,4>octan-6-yl acetate 
• 5257-38-5 (+/-)-exo-5-acetoxybicyclo<2.2.1>heptan-2-one 
• 5763-72-4 (+/-)-2endo,6endo-epoxido-norbornane-3exo-ol 
• 7329-28-4 (1RS,2RS,4SR,5SR,6RS)-3-oxatricyclo<3.2.1.0^2,4>octan-6-ol 

Downstream Products

• 27943-47-1 norbornane-2,5-dione 
• 145092-68-8 (S,S)-bicyclo<2.2.1>heptane-2,5-dione 
• 1384282-27-2 (1S,2S,4S,5S)-N₂,N₅-dibenzyl-N₂,N₅-dimethylbicyclo[2.2.1]heptane-2,5-diamine 
• 698353-48-9 C₂₁H₂₆N₂ 
• 110354-77-3 exo-5-benzyloxybicyclo<2.2.1>heptan-2-one 
• 539834-16-7 2,2'-[(1S,2S,4S,5S)-bicyclo[2.2.1]heptane-2,5-diylbis(nitrilomethylidyne)]bis(4,6-di-tert-butylphenol) 
• 698353-42-3 (1S,2S,4S,5S)-2,5-diamino-bicyclo[2.2.1]heptane 

Relevant articles and documents

Evaluation of the chiral DIANANE backbone as ligand for organolithium reagents

Novel endo,endo-2,5-diaminonorbonane-derived tertiary C2- symmetrical diamines were synthesized via the one-pot reductive amination of enantiomerically pure norbornane-2,5-dione. These ligands were applied to various catalytic reactions such as asymmetric deprotonation, asymmetric bromine-lithium exchange, and enantioselective addition of aryl- and allkylithium reagents to aromatic aldimines. Copyright

Enantioselective Synthesis of DIANANE, a Novel C2-Symmetric Chiral Diamine for Asymmetric Catalysis

DIANANE (endo,endo-2,5-diaminonorbornane) is a novel chiral C 2-symmetric diamine, based on the rigid bicyclo[2.2.1]heptane scaffold. Schiff-base ligands derived from DIANANE have already found use in asymmetric catalysis, e.g., in the highly e

Syntheses in the isocamphane series XLII [1]. Synthesis and odour of 5-exo-hydroxycamphene (isonojigiku alcohol)

The synthesis of the title compound is described. Hydroxylation of the endocyclic double bond of 2-acetyl-3,3-dimethylnorborn-5-ene furnished a mixture of nojigiku alcohol and the title compound. A shorter route leads from 2,5-norbornadiene solely to the desired camphoraceous smelling new hydroxy derivative to which the name isonojigiku alcohol is assigned.