21467-13-0

Basic information

• Product Name: 2-(2-benzyloxycarbonylamino-3-carbamoylpropionylamino)-3-phenylpropionic acid tert-butyl ester
• Synonyms: 2-(2-benzyloxycarbonylamino-3-carbamoylpropionylamino)-3-phenylpropionic acid tert-butyl ester
• CAS NO: 21467-13-0
• Molecular Weight: 469.538
• Mol File: 21467-13-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-benzyloxycarbonylamino-3-carbamoylpropionylamino)-3-phenylpropionic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-benzyloxycarbonylamino-3-carbamoylpropionylamino)-3-phenylpropionic acid tert-butyl ester(21467-13-0)
• EPA Substance Registry System: 2-(2-benzyloxycarbonylamino-3-carbamoylpropionylamino)-3-phenylpropionic acid tert-butyl ester(21467-13-0)

Safety Data

• Hazardous Substances Data: 21467-13-0(Hazardous Substances Data)

Upstream product

• 16874-17-2 L-phenylalanine tert-butyl ester 
• 2304-96-3 N-benzyloxycarbonyl-L-asparagine 

Downstream Products

• 688763-60-2 2-(2-amino-3-carbamoylpropionylamino)-3-phenylpropionic acid tert-butyl ester 

Relevant articles and documents

Development of low molecular weight HIV-1 protease dimerization inhibitors

The role of HIV protease in viral replication has made it a significant target for inhibition. The focus of our studies is to target the dimerization interface of HIV-1 protease because disruption of the dimer will inhibit enzymatic activity. The initial strategy began with cross-linked peptides derived from the interface of HIV protease. Herein we describe the design of a focused library of agents based on a minimal pharmacophore for HIV-1 protease dimerization inhibition.