214690-17-2Relevant articles and documents
Hit-to-lead optimization of phenylsulfonyl hydrazides for a potent suppressor of PGE2 production: Synthesis, biological activity, and molecular docking study
Kim, Minju,Lee, Sunhoe,Park, Eun Beul,Kim, Kwang Jong,Lee, Hwi Ho,Shin, Ji-Sun,Fischer, Katrin,Koeberle, Andreas,Werz, Oliver,Lee, Kyung-Tae,Lee, Jae Yeol
, p. 94 - 99 (2015/12/18)
Preliminary hit-to-lead optimization of a novel series of phenylsulfonyl hydrazide derivatives, which were derived from the high throughput screening hit compound 1 (IC50 = 5700 nM against PGE2 production), for a potent suppressor of