214848-52-9

Basic information

• Product Name: 4-Piperidinecarbonitrile, 4-(4-chlorophenyl)-1-(phenylmethyl)-
• CAS NO: 214848-52-9
• Molecular Formula: C19H19ClN2
• Molecular Weight: 310.826
• Mol File: 214848-52-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-Piperidinecarbonitrile, 4-(4-chlorophenyl)-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinecarbonitrile, 4-(4-chlorophenyl)-1-(phenylmethyl)-(214848-52-9)
• EPA Substance Registry System: 4-Piperidinecarbonitrile, 4-(4-chlorophenyl)-1-(phenylmethyl)-(214848-52-9)

Safety Data

• Hazardous Substances Data: 214848-52-9(Hazardous Substances Data)

Upstream product

• 10429-82-0 N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine hydrochloride 
• 140-53-4 p-chlorobenzyl cyanide 

Downstream Products

• 660844-73-5 [1-benzyl-4-(4-chloro-phenyl)-piperidin-4-yl]-methanol 
• 672927-27-4 [4-(4-chloro-phenyl)-piperidin-4-yl]-methanol 
• 735225-04-4 4-(4'-chlorophenyl)-4-carboxy-1-benzylpiperidine 

Relevant articles and documents

4-ARYLMORPHOLIN-3-ONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF

The invention relates to compounds corresponding to formula (I): in which: Ar represents a mono- or disubstituted phenyl; R1 represents an unsubstituted or substituted phenyl; R2 represents: a pyridyl; an unsubstituted or substituted phenyl; a benzyl that is unsubstituted or substituted on the phenyl; R2 may moreover represent: a heterocyclic radical; R3 represents various values. The invention also comprises methods for the compounds preparation, formulations comprising them and therapeutic applications thereof.

SUBSTITUTED PYRROLIDIN-3-YL-ALKYL-PIPERIDINES

The present invention relates to substituted pyrrolidinyl-3-yl-alkyl-piperidines, their stereoisomers, and pharmaceutically acceptable salts thereof and processes for preparation of the same. The compounds of the present invention are useful in their pharmacological activities such as tachykinin antagonism, especially substance P and neurokinin A antagonism, and the like. Compounds having the property of tachykinin antagonism are indicated for conditions associated with neurogenic inflammation and other diseases described herein.