214852-60-5 Usage
Uses
Used in Pharmaceutical Industry:
(2R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-[[(phenylmethoxy)carbonyl]amino]butanoic acid is used as a potential pharmaceutical compound for its unique structure and functional groups, which may contribute to the development of new drugs or therapeutic agents.
Used in Biochemical Research:
In biochemical research, (2R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-[[(phenylmethoxy)carbonyl]amino]butanoic acid can be utilized as a building block or a component in the synthesis of more complex molecules, facilitating the study of biological processes and the development of novel biochemical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 214852-60-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,4,8,5 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 214852-60:
(8*2)+(7*1)+(6*4)+(5*8)+(4*5)+(3*2)+(2*6)+(1*0)=125
125 % 10 = 5
So 214852-60-5 is a valid CAS Registry Number.
InChI:InChI=1S/C17H24N2O6/c1-17(2,3)25-15(22)18-10-9-13(14(20)21)19-16(23)24-11-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3,(H,18,22)(H,19,23)(H,20,21)/t13-/m1/s1
214852-60-5Relevant academic research and scientific papers
Exploratory solid-phase synthesis of factor Xa inhibitors: Discovery and application of P3-heterocyclic amides as novel types of non-basic arginine surrogates
Ho, Jonathan Z.,Levy, Odile E.,Gibson, Tony S.,Nguyen, Khanh,Semple, J. Edward
, p. 3459 - 3464 (2007/10/03)
A series of novel FXa inhibitors 2a-m and 3a-f was discovered that feature heterocyclic carboxamides tethered to a d-diaminobutyric acid sidechain. These neutral amide derivatives serve as novel P3 d-arginine mimics. Pyrazine carboxamide scaffolds afforded the most potent FXa inhibitors (e.g., 2b IC50 = 4.6 nM). The synthesis and biological activity of two focused libraries are reported.
