21487-50-3

Basic information

• Product Name: 1-phenyl-3-(4-nitrophenyl)-1H-pyrazole-4-carboxaldehyde semicarbazone
• CAS NO: 21487-50-3
• Molecular Weight: 350.337
• Mol File: 21487-50-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-phenyl-3-(4-nitrophenyl)-1H-pyrazole-4-carboxaldehyde semicarbazone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-3-(4-nitrophenyl)-1H-pyrazole-4-carboxaldehyde semicarbazone(21487-50-3)
• EPA Substance Registry System: 1-phenyl-3-(4-nitrophenyl)-1H-pyrazole-4-carboxaldehyde semicarbazone(21487-50-3)

Safety Data

• Hazardous Substances Data: 21487-50-3(Hazardous Substances Data)

Upstream product

• 563-41-7 semicarbazide hydrochloride 
• 68-12-2 N,N-dimethyl-formamide 
• 77635-72-4 1-(4-nitro-phenyl)-ethanone-phenylhydrazone 
• 21487-49-0 3-(4-nitrophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde 

Relevant articles and documents

One-pot synthesis of some new semicarbazone, thiosemicarbazone, and hydrazone derivatives of 1-phenyl-3-arylpyrazole-4-carboxaldehyde from acetophenone phenylhydrazones using Vilsmeier-Haack reagent

Semicarbazone derivatives 3 of 1,3-diphenylpyrazole-4-carboxaldehyde have been synthesized in high yields through a one-pot procedure involving acetophenone phenylhydrazones 1 subjected to Vilsmeier double formylation and workup under new conditions (i.e., treatment with semicarbazide followed by sodium bicarbonate). This method is even suitable for preparing other derivatives (i.e., thiosemicarbazones 4 and hydrazones 5) in high yields. Copyright Taylor & Francis Group, LLC.