214913-86-7

Basic information

• Product Name: 6-{3-[1-(2-hydroxymethyl-phenyl)-1H-imidazol-2-ylsulfanyl]-propoxy}-1H-quinolin-2-one
• CAS NO: 214913-86-7
• Molecular Weight: 407.493
• Mol File: 214913-86-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-{3-[1-(2-hydroxymethyl-phenyl)-1H-imidazol-2-ylsulfanyl]-propoxy}-1H-quinolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-{3-[1-(2-hydroxymethyl-phenyl)-1H-imidazol-2-ylsulfanyl]-propoxy}-1H-quinolin-2-one(214913-86-7)
• EPA Substance Registry System: 6-{3-[1-(2-hydroxymethyl-phenyl)-1H-imidazol-2-ylsulfanyl]-propoxy}-1H-quinolin-2-one(214913-86-7)

Safety Data

• Hazardous Substances Data: 214913-86-7(Hazardous Substances Data)

Upstream product

• 214914-12-2 1-allyloxymethyl-2-isothiocyanato-benzene 
• 214914-15-5 1-{2-[((E)-Propenyl)oxymethyl]-phenyl}-1H-imidazole-2-thiol 
• 214914-13-3 1-(2-allyloxymethyl-phenyl)-3-(2,2-diethoxy-ethyl)-thiourea 
• 214914-14-4 1-(2-allyloxymethyl-phenyl)-1H-imidazole-2-thiol 
• 214914-31-5 2-(prop-2-enyloxymethyl)benzenamine 

Downstream Products

• 214913-89-0 6-{3-[1-(2-hydroxymethyl-phenyl)-1H-imidazole-2-sulfinyl]-propoxy}-1H-quinolin-2-one 
• 214914-08-6 Acetic acid 2-{2-[(S)-3-(2-oxo-1,2-dihydro-quinolin-6-yloxy)-propane-1-sulfinyl]-imidazol-1-yl}-benzyl ester 

Relevant articles and documents

An efficient synthesis of optically active metabolites of platelet adhesion inhibitor OPC-29030 by lipase-catalyzed enantioselective transesterification

The optically active metabolites of (S)-3,4-dihydro-6-[3-(1-o-tolyl-2- imidazolyl)sulfinylpropoxy]-2(1H)-quinolinone (OPC-29030, 1), which is a new anti-platelet agent (platelet adhesion inhibitor), were effectively synthesized by the enzyme-catalyzed enantioselective transesterification of the racemic sulfinyl metabolites. The enzymes can recognize a stereogenic sulfur atom remote from the reaction site.