214978-13-9Relevant academic research and scientific papers
N -heterocyclic carbene-catalyzed internal redox reaction of alkynals: An efficient synthesis of allenoates
Zhao, Yu-Ming,Tam, Yik,Wang, Yu-Jie,Li, Zigang,Sun, Jianwei
supporting information; experimental part, p. 1398 - 1401 (2012/06/01)
An efficient N-heterocyclic carbene (NHC)-catalyzed internal redox reaction of alkynals that bear a γ leaving group has been developed. This process provides a new access to a range of allenoates in good yields. Preliminary results demonstrate that the en
Spirodiepoxide-based cascades: Direct access to diverse motifs
Sharma, Rojita,Manpadi, Madhuri,Zhang, Yue,Kim, Hiyun,Ahkmedov, Novruz G.,Williams, Lawrence J.
supporting information; experimental part, p. 3352 - 3355 (2011/08/22)
Allene epoxide formation/opening reaction sequences enabled direct access to diverse products. Described here are a single flask procedure for allene preparation and allene oxidation/derivatization reactions that give, among others, diendiol, diyndiol, α′-hydroxy-γ-enone, dihydrofuranone, butenolide, and δ-lactone products.
Stereoselective syntheses of trisubstituted olefins via platinum catalysis: α-Silylenones with geometrical complementarity
Rooke, Douglas A.,Ferreira, Eric M.
supporting information; experimental part, p. 11926 - 11928 (2010/11/16)
The stereoselective syntheses of α-silylenones using catalytic PtCl2 are reported. Via alkyne activation, α- hydroxypropargylsilanes are converted to (Z)-silylenones through a highly selective silicon migration. The complementary (E)-silylenone
Stereoselective dichlorination of allylic alcohol derivatives to access key stereochemical arrays of the chlorosulfolipids
Shibuya, Grant M.,Kanady, Jacob S.,Vanderwal, Christopher D.
supporting information; experimental part, p. 12514 - 12518 (2009/02/05)
Dichlorination of (Z)-allylic trichloroacetates efficiently and stereoselectively generates the syn,syn hydroxydichloride stereotriad that is prevalent in the understudied polychlorinated sulfolipid class of natural products. Further, the dichlorination of a (2)-allylic chlorohydrin affords with high selectivity a stereotetrad present in one of the chlorosulfolipids.
