215095-77-5 Usage
Uses
Used in Dermatological Applications:
Triamcinolone is used as a topical treatment for various skin conditions, including eczema, psoriasis, and contact dermatitis. It is applied as a cream or ointment to the affected areas, helping to alleviate itching, redness, and swelling.
Used in Allergy and Inflammatory Disorder Treatment:
Triamcinolone is used as an oral medication or injection to treat severe allergies and inflammatory disorders, such as asthma, rheumatoid arthritis, and lupus. It helps to suppress the immune system's overactive response, reducing inflammation and alleviating symptoms.
Used in Ophthalmic Applications:
In ophthalmology, triamcinolone is used as an intravitreal implant or injection to treat eye conditions such as uveitis and macular edema. It helps to reduce inflammation and swelling in the eye, improving vision and preventing further damage.
Used in Ear, Nose, and Throat (ENT) Applications:
Triamcinolone is used as an aerosol or nasal spray to treat conditions such as nasal polyps, sinusitis, and allergic rhinitis. It helps to reduce inflammation and congestion in the nasal passages, providing relief from symptoms.
Check Digit Verification of cas no
The CAS Registry Mumber 215095-77-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,5,0,9 and 5 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 215095-77:
(8*2)+(7*1)+(6*5)+(5*0)+(4*9)+(3*5)+(2*7)+(1*7)=125
125 % 10 = 5
So 215095-77-5 is a valid CAS Registry Number.
InChI:InChI=1/C21H26O6/c1-18-6-5-12(23)7-11(18)3-4-13-14-8-15(24)20(26,16(25)10-22)19(14,2)9-17-21(13,18)27-17/h5-7,13-15,17,22,24,26H,3-4,8-10H2,1-2H3/t13-,14-,15+,17?,18-,19-,20-,21?/m0/s1
215095-77-5Relevant academic research and scientific papers
Preparation process of triamcinolone acetonide
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Paragraph 0008, (2017/07/21)
The invention relates to a preparation process of triamcinolone acetonide. The triamcinolone acetonide is prepared by taking an intermediate III as a raw material. The preparation process comprises the following steps of: by taking a hydrofluoric acid-acetone mixed solvent as a solvent, slowly adding the intermediate III in a temperature range of 40 DEG C below zero to 30 DEG C below zero; after adding the raw material, performing a reaction for 4-8 hours; returning the temperature to 5 DEG C below zero to zero DEG C, and continuously performing a reaction for 10-30 min; after reaction, slowly adding the reaction liquid into a potassium carbonate solution; adjusting the PH value to 7.0-7.5; filtering and discharging the material; and drying the same to obtain triamcinolone acetonide. The preparation process shortens the production period, prevents use of a lot of high-matching acetone and is more environmentally friendly.
