215180-60-2Relevant academic research and scientific papers
On the stereoselectivity in bisdihydroxylation of 1,5-cyclooctadiene with osmium tetroxide
Kawazoe,Furusho,Nakanishi,Takata
, p. 2107 - 2112 (2001)
In the bisdihydroxylation of 1,5-cyclooctadiene with OsO4, use of a stoichiometric amount of OsO4 yielded a 1:1 mixture of syn- and anti-isomers, while use of a catalytic amount of OsO4 gave only syn-(1R*,2S*,5R*,6S*)-cyclooctane-1,2,5,6-tetrol. This syn-selectivity was attributed to the favorable formation of an intramolecular osmium(VI) bisglycolate ester in the catalytic reaction.
