215191-58-5Relevant academic research and scientific papers
Synthesis and alkylation of spiro-2-oxazolines containing fused 3,4-dihydropyrazin-2(1H)-ones
Music, Irena,Vercek, Bojan
experimental part, p. 2353 - 2364 (2011/11/29)
Spiro-2-oxazolines containing 3,4-dihydroquinoxalin-2(1H)-one, 3,4-dihydrobenzoquinoxalin-2(1H)-one, 1,2-dihydropyrido[2,3-b]pyrazin-3(4H)- one or 5,6-dihydropteridin-7(8H)-one moiety were prepared by heating of aromatic or heteroaromatic diamines with 2-benzoylamino-3-chloropropenoic acid in the presence of triethylamine. Treatment of spiro-2-oxazolines with MeI or EtBr using Bu4NHSO4 and K2CO3 introduced the methyl or ethyl group on the lactam nitrogen atom.
